Four temporin-derived peptides exhibit antimicrobial and antibiofilm activities against methicillin-resistant Staphylococcus aureus
Temporin-GHa (GHa) was cloned from Hylarana guentheri, showing a weak antimicrobial activity.In order to improve its bactericidal efficacy, GHaR6R, GHaR7R, GHaR8R and ornament ice cube molds GHaR9W were designed and synthesized.Compared to the parent peptide, the GHa-derived peptides show potent antimicrobial activities against methicillin-resistan